Echinacea Extract 500mg

No significant herb-drug interactions with echinacea have been reported. Based on in vitro studies, echinacea may be a mild inhibitor of the cytochrome P450 3A4 enzyme complex system; this inhibition tends to increase levels of drugs metabolized by this system, such as itraconazole (Sporanox), fexofenadine (Allegra), and lovastatin (Mevacor).11 Although no such interaction has been reported in humans, it is probably advisable to use echinacea with caution in patients who are taking these medications. Theoretically, the immune-stimulating properties of echinacea might interfere with the use of immunosuppressive medications in patients with autoimmune disease; however, while such an effect is theoretically possible, it has not been documented in animals or humans.