Anatrin - Fibromyalgia pain and fatigue relief

• Overview
• Ingredients
• Reviews
• Q & A's

Product Description

Then Read This!

For persons suffering from Fibromyalgia, nutritional strategies are critical for lessening the severity of this debilitating syndrome. With ingredients backed by science and supported by top FM physicians and experts, Anatrin has been designed to support all Fibromyalgia sufferers - regardless of individual severity.

About Fibromyalgia

Fibromyalgia is an extremely difficult condition to diagnose, and treat for that matter. Its origin is remains misunderstood, despite the fact the some 3 to 6 million Americans suffer from this condition. That equates to approximately one in every 50 people. Additionally, this does not account for persons that have yet to be definitively diagnosed and may be currently suffering from this affliction. People with fibromyalgia may look well, but feel miserable.

People may not appreciate what a sufferer is going through and persons are often criticized for suffering from an "imagined" illness. If this condition remains unrecognized or is not addressed by therapies other than conventional treatments, it can wreak havoc on all areas of a person's life; including social, professional, and psychological well being.

What Is Fibromyalgia?

Fibromyalgia is a chronic disorder that is characterised by point-specific muscle pain, tenderness, and fatigue. These points are located on both the upper and lower body (see picture above); responding to pain from even the slightest of applied pressure. Some practitioners consider fibromyalgia an arthritis-related condition. However, it is important to understand that arthritis causes inflammation and damage to the joints, muscles, or other important body tissues; fibromyalgia does not. Its cause is also unknown.

Some physicians believe that fibromyalgia may be the end result of a stressful or emotionally traumatic experience. Yet other practitioners think it may be linked to illness or repetitive injury. Regardless of these opinions, fibromyalgia can be considered a syndrome rather than a disease as its signs, symptoms, and medical problems are sporadic and not related to a single, identifiable cause.

Signs and Symptoms:

The primary signs and symptoms of fibromyalgia often resemble those of another condition, rheumatoid arthritis (RA). Like arthritis, fibromyalgia also presents with pain, stiffness, fatigue. However, fibromyalgia sufferers usually present secondary symptoms that are not muscle or joint related. Listed below are the most typical primary and secondary symptoms:

• Sleep disturbances
• Morning stiffness
• Headaches
• Irritable bowel syndrome
• Painful menstrual periods
• Numbness or tingling of the extremities
• Restless legs syndrome
• Temperature sensitivity
• Cognitive and memory problems (sometimes referred to as "fibro fog")
• A variety of other symptoms

Of all individuals diagnosed with fibromyalgia, 80 - 90 percent of patients are women of childbearing age. Men, children, and the elderly account for the remaining 10 - 20 percent.

Standard Treatments:

Treatment of fibromyalgia is difficult because, again, the cause is still not known. Therefore there is no target for treatment, except for addressing underlying disease conditions. Relaxation techniques, stress reduction, exercise, sleep therapy, stretching, massage, and hot and cold applications are all recommended to treat the pain and stiffness associated with fibromyalgia. Prescription medications can be useful to treat insomnia (anti-depressant medications), pain (corticosteroid injections), and depression (SSRIs).

Alternative therapies may also provide some use, as they focus on underlying factors that can contribute to the development of fibromyalgia, such as nutrient deficiencies, oxidative stress, and neurotransmitter disregulation.

Existing literature confirms the deficiencies of; intracellular magnesium, B12, whole body potassium, and intracellular ATP. In addition to these dietary inadequacies, persons with fibromyalgia often have problems regulating sleep patterns. Anatrin not only addresses primary nutrient-based deficiencies, it also helps to regulate sleeping patterns and enhance serotonin levels while boosting intracellular ATP. In fact, many top physicians who regularly treat FM recommend the same ingredients found in Anatrin, as each is backed by extensive scientific study.

Product Reviews

Questions and Answers

Ingredients

Anatrin Research

• Magnesium - In patients with fibromyaliga, magnesium levels are often found to be low or deficient when compared with subjects who do not have symptoms of fibromyalgia ( 1 ). Some patients may show normal serum levels of magnesium, but intracellular levels are often deficient ( 2 ). A blend of intravenously injected vitamins and minerals, called a Myer's Cocktail, containing high amounts of magnesium has resulted in decreased and even complete resolution of fibromylagia symptoms ( 3 ). IM and IV Magnesium given alone have demonstrated effectiveness in reducing chronic muscle complaints ( 4 ).
• Ascorbigen and Broccoli Powder - Ascorbigen is one of the most common medicinal compounds, called indoles, released when cruciferous vegetables are cooked. These types of indoles can induce Phase I detoxification in the liver ( 5 ). A clinical trial was conducted at National College of Naturopathic Medicine in Portland , Oregon where patients with fibromyalgia were given both 100 mg of ascorbigen powder and 400 mg of broccoli powder for one month. Patients experienced a significant reduction in both physical impairment and total fibromylagia impact scores ( 6 ).
• Rhodiola rosea Extract - Rhodiola is a medicinal plant that is used clinically to treat functional fatigue and mild cognitive decline. The compounds in this plant have been shown to increase ATP production ( 7 ). This is particularly helpful in fibromyalgia because ATP availability is important for working muscle and preventing fatigue.
• Ginger root Extract - Ginger is an herb with a long history of use throughout Asia and ancient Greece for rheumatic disorders. A clinical trial of patients with rheumatoid arthritis, osteoarthritis and muscular discomfort demonstrated relief of pain with dried ginger consumption in all patients with muscle pain ( 8 ). As well case histories from patients with rheumatoid arthritis who have used ginger as an adjunct treatment cite additional relief over conventional medication alone ( 9 ).
• 5-HTP - A number of clinical studies have examined the role of serotonin and the precursor, 5-HTP, in patients with fibromylagia. One clinical trial involved a 90 day trial of supplementation with 5-HTP in patients with fibromyalgia. Nearly 50% of patients investigators noted a good or fair clinical improvement in symptoms such as number of tender points, anxiety, pain intensity, quality of sleep and fatigue ( 10 ). Another double blind placebo controlled trial also showed that all clinical parameters studied were significantly improved by treatment with 5-HTP when compared to placebo ( 11 ).
• Melatonin - Melatonin is a naturally produced biochemical that is secreted from the pineal gland at the base of the brain, which controls circadian rhythms and plays a major role in sleep cycles. Numerous studies have shown a link between melatonin levels in patients with fibromyalgia. Typically patients with fibromyalgia have lowered secretion of melatonin at night, which may partially explain impaired sleep at night, fatigue during the day, and changed pain perception ( 12 ). A clinical trial demonstrated that supplementation at bedtime with melatonin can significantly improve tender point count, severity of pain and sleep ( 13 ).
• Malic Acid - Malic acid is a naturally occurring chemical found most notably in apple juice. It helps improve absorption of some nutrients like magnesium. A randomized double blind placebo controlled trial showed that supplementation with a proprietary tablet of malic acid and magnesium, given at a high dose over 6 months resulted in s ignificant reductions in the severity of all 3 primary pain/tenderness measures without adverse effects ( 14 ).

Anatrin Research

1 . Ng SY. Hair calcium and magnesium levels in patie nts with fibromyalgia: a case center study. J Manipulative Physiol Ther 1999;22(9):586-93.
2 . Moorkens G et al. Magnesium deficit in a sample of the Belgian population presenting with chronic fatigue. Magnes Res 1997;10:329-337.
3 . Gaby AR. Intravenous Nutrient Therapy: the Myers' Cocktail". Altern Med Rev 2002;7(5)389-403
4 . Reed JC. Magnesium therapy in musculoskeletal pain syndromes- retrospective review of clinical results. MagnesTrace Elem 1990;9:330.
5 . Manson M et al. Mechanism of action of dietary chemoprotective agents in rat liver: induction of phase I and phase II drug metabolizing enzymes and aflatoxin B1 metabolism. Carcinogenesis 1997;18:1729-1738.
6 . Bramwell B et al. The Use of Ascorbigen in the Treatment of Patients with Fibromyalgia: A Preliminary Trial. Altern Med Rev 2000;5(5):455-462
7 . Abidov M et al. Effect of extracts from Rhodiola rosea and Rhodiola crenulata (Crassulaceae) roots on ATP content in mitochondria of skeletal muscles. Bull Exp Biol Med. 2003 Dec;136(6):585-7.
8 . Srivastava KC and Mustafa T. Med Hypotheses 1992;39(4):342-348.
9 . Srivastava KC and Mustafa T. Med Hypotheses 1989;29(1)25-28.
10 . Puttini PS and Caruso I. Primary fibromyalgia syndrome and 5-hydroxy-L-tryptophan: a 90-day open study.J Int Med Res. 1992;20(2):182-9
11 . Caruso I et al. All the clinical parameters studied were significantly improved by treatment with 5-HTP. J Int Med Res. 1990;18(3):201-9.
12 . Wikner J et al. Fibromyalgia--a syndrome associated with decreased nocturnal melatonin secretion. Clin Endocrinol (Oxf). 1998;49(2):179-83.
13 . Citera G et al. The effect of melatonin in patients with fibromyalgia: a pilot study. Clin Rheumatol. 2000;19(1):9-13
14 . Russell IJ et al. Clin Endocrinol (Oxf). J Rheumatol. 1995;22(5):953-8. 1998 Aug;49(2):179-83.